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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPTY2D1
All Species:
22.12
Human Site:
Y630
Identified Species:
40.56
UniProt:
Q68D10
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68D10
NP_919261.2
685
75546
Y630
F
G
Y
D
R
K
K
Y
K
D
E
S
D
Y
A
Chimpanzee
Pan troglodytes
XP_508321
684
75407
Y629
F
G
Y
D
R
K
K
Y
K
D
E
S
D
Y
A
Rhesus Macaque
Macaca mulatta
XP_001082108
684
75599
Y629
F
G
Y
D
R
K
K
Y
K
D
E
S
D
Y
A
Dog
Lupus familis
XP_534086
793
86791
Q757
E
S
S
W
K
E
Q
Q
K
E
E
A
K
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q68FG3
682
74799
Q646
E
S
S
W
K
E
Q
Q
K
E
E
A
K
S
L
Rat
Rattus norvegicus
XP_002725626
681
74519
Q645
E
S
S
W
K
E
Q
Q
K
E
E
A
K
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517926
644
69600
Y589
F
G
Y
D
R
K
K
Y
K
D
E
S
D
Y
A
Chicken
Gallus gallus
XP_421015
633
66869
D593
V
G
Y
K
R
Q
I
D
D
D
D
D
D
D
E
Frog
Xenopus laevis
Q6NU13
800
83727
Y740
F
G
Y
D
R
N
R
Y
R
D
E
S
D
Y
A
Zebra Danio
Brachydanio rerio
Q6DGN6
629
69420
Q595
E
S
S
W
K
E
Q
Q
K
E
E
A
R
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IMP6
581
65683
S549
V
Q
R
E
E
F
I
S
K
K
L
G
M
Q
E
Honey Bee
Apis mellifera
XP_395689
579
67372
V547
Q
Q
L
K
E
E
Y
V
S
T
K
I
G
I
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793115
639
72247
Y584
F
G
Y
D
K
S
K
Y
G
Y
E
S
D
F
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.7
73.6
N.A.
80.5
82.1
N.A.
55.6
47.8
43
42.7
N.A.
28.3
23.2
N.A.
24
Protein Similarity:
100
99.5
98.5
78.8
N.A.
89.9
90.3
N.A.
66.5
58
56.6
58.6
N.A.
44.2
41.6
N.A.
39.8
P-Site Identity:
100
100
100
13.3
N.A.
13.3
13.3
N.A.
100
33.3
80
13.3
N.A.
6.6
0
N.A.
66.6
P-Site Similarity:
100
100
100
46.6
N.A.
46.6
46.6
N.A.
100
46.6
93.3
46.6
N.A.
13.3
13.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
31
0
0
47
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
47
0
0
0
8
8
47
8
8
54
8
0
% D
% Glu:
31
0
0
8
16
39
0
0
0
31
77
0
0
0
16
% E
% Phe:
47
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
54
0
0
0
0
0
0
8
0
0
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
16
0
0
0
0
8
0
8
0
% I
% Lys:
0
0
0
16
39
31
39
0
70
8
8
0
24
0
0
% K
% Leu:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
31
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
16
0
0
0
8
31
31
0
0
0
0
0
8
0
% Q
% Arg:
0
0
8
0
47
0
8
0
8
0
0
0
8
0
0
% R
% Ser:
0
31
31
0
0
8
0
8
8
0
0
47
0
31
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% T
% Val:
16
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
31
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
54
0
0
0
8
47
0
8
0
0
0
39
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _